The Division of Clinical and Translational Research (DoCTR) is the home for patient-oriented research in the Department of Anesthesiology. Numerous translational and clinical research projects are currently led by faculty members in the division, in a wide variety of research areas such as:
- perioperative outcomes,
- postoperative delirium,
- functional neuroimaging of anesthesia and drug disposition,
- novel treatments for neuropathic pain, including for pain associated with diabetes, cancer, and anticancer chemotherapy
- cognitive dysfunction and chronic pain,
- pediatric postoperative pain and analgesic pharmacology
- postoperative patient-reported outcomes,
- perioperative mental health,
- machine learning and artificial intelligence,
- human factors,
- persistent post-surgical pain,
- the role of microbiome in chronic pain
- perioperative and peripartum sleep apnea,
- integration of electronic health information to optimize safety and outcomes.
All division’s investigators have clinical research programs and some also have laboratory-based translational programs.
DoCTR has several full-time faculty members as well as affiliated faculty and employs full-time research coordinators, nurses, and regulatory/QA specialists for human subject research. Support for all aspects of clinical research is also offered including study design, protocol development, IRB and regulatory document preparation and submission, recruitment, monitoring, data management, and analysis.
The Division is led by Simon Haroutounian, PhD, an experienced clinical and translational scientist in the field of clinical trials and perioperative outcomes. Dr. Haroutounian is also the Chief of Clinical Pain Research and provides a robust research bridge between DoCTR and the Washington University Pain Center.
Robert Gereau, PhD, Dr. Seymour and Rose T. Brown Professor of Anesthesiology, is the Department’s Vice Chair for Research and also leads Washington University Pain Center.
Jose Moron-Concepcion, PhD, is the Chief of the Division of Basic Science Research.
Gereau, Haroutounian, and Moron-Concepcion jointly provide research oversight for the Department and are committed to team science and vibrant intra- and interdepartmental collaborations.