Brian Ruyle, PhD, a postdoctoral fellow in the Moron-Concepcion Lab, has been selected to present his research on opioid-induced respiratory depression at the 17th Annual Countermeasures Against Chemical Threats (CounterACT) Network Research Symposium. Additionally, he is one of just 10 trainees awarded a travel grant, providing him with the necessary funds to attend the event in Salt Lake City, Utah, on June 3-5, 2024.
Ruyle’s research focuses on unraveling the mechanisms by which ultrapotent synthetic opioids, including fentanyl, induce severe cardiorespiratory depression. As the lead investigator on this project, he aims to enhance the understanding of how opioids interact with central and peripheral opioid receptors, ultimately paving the way for improved treatment strategies for individuals with opioid use disorders.
“Presenting our findings at the CounterACT Symposium is not just an honor but a vital opportunity to collaborate and accelerate progress in our fight against opioid misuse,” says Ruyle.
This marks a significant milestone for the Moron-Concepcion Lab as they prepare to share their latest findings with a diverse audience beyond the realm of neuroscience. By shedding light on the neural pathways underlying opioid-induced respiratory depression, Ruyle’s work has the potential to drive advancements in the field, moving us closer to reducing the harmful effects of opioid misuse.
“Our goal is to go beyond the laboratory and make a tangible impact on public health policy and clinical practices,” Dr. Ruyle explains. “Understanding the precise mechanisms of opioid-induced respiratory depression is key to developing safer pain management strategies.”
With a PhD in Biomedical Sciences from the University of Missouri, Ruyle brings a wealth of expertise and dedication to his research endeavors. His previous work on arterial chemoreflex neurocircuitry has laid a solid foundation for his current research, positioning him as expert in this critical area of study.
“Each day in the lab brings us closer to unraveling the complex interactions at play in opioid receptors,” Ruyle continued. “It’s about piecing together a puzzle that could one day save countless lives.”
Stay tuned for updates as Ruyle presents the findings from his research, showcasing the groundbreaking work happening in the Moron-Concepcion Lab in the fight against opioid misuse.