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Lara Crock, MD, PhD, Receives 2019 IARS 2019 Mentored Research Award

Laura Crock

Lara Crock, MD, PhD

Dr. Crock is studying whether the gut microbiome influences development and recovery from complex regional pain syndrome (CRPS), a debilitating condition of unknown etiology that develops following surgery or trauma. Patients with a history of CRPS are difficult in terms of anesthesiology and pain management because they are more likely to redevelop CRPS or have uncontrolled post-operative pain when they undergo surgical procedures.

In Dr. Crock’s pain management clinic, around 50% of patients recover if treated within one year. Those who do not are permanently disabled, requiring extensive treatments including long-term opioids. Interestingly, some patients with CRPS have recovered following antibiotic treatment. Further, mouse models suggest a crucial role of the gut microbiome in the development of pain. With improved understanding of associated triggers and biomarkers, Dr. Crock’s research has the potential to develop innovative non-opioid treatment modalities targeting the microbiome to treat and prevent development of chronic pain.

Congratulations to Dr. Lara Crock!